Abstract #4381
Differentiation of High-grade and Low-grade Diffuse Gliomas by Intravoxel Incoherent Motion MRI
Osamu Togao 1 , Akio Hiwatashi 1 , Koji Yamashita 1 , Kazufumi Kikuchi 1 , Marc Van Cauteren 2 , and Hiroshi Honda 1
1
Clinical Radiology, Graduate School of
Medical Sciences, Kyushu University, Fukuoka, Fukuoka,
Japan,
2
Philips
Electronics Japan, Tokyo, Japan
Intravoxel incoherent motion (IVIM) has been proposed as
a method to measure diffusion and perfusion using a
single diffusion-weighted acquisition scheme. The both
diffusion and perfusion properties are major features in
determining glioma grades. In this study, we
prospectively evaluated the diagnostic performance of
IVIM parameters in differentiating high-grade gliomas
(HGGs) from low-grade gliomas (LGGs). Both true
diffusion D and perfusion fracture f were useful in the
differentiation, and f showed the best diagnostic
performance. IVIM imaging can be used as a noninvasive
quantitative imaging method in differentiating HGG from
LGG.
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