Abstract #4361
A comparison of FLAIR* and T2*-weighted imaging in detecting white matter lesions and central veins in patients with MS and ischaemic lesions at 3T.
Amal Samaraweera 1 , Margareta Clarke 2 , Olivier Mougin 3 , Rob Dineen 4 , Ian Driver 3 , Paul S Morgan 5 , and Nikos Evangelou 1
1
Division of Clinical Neuroscience,
University of Nottingham, Nottingham, United Kingdom,
2
Clinical
Neurology, Nottingham University Hospitals NHS Trust,
Nottingham, United Kingdom,
3
Sir
Peter Mansfield MR Centre, University of Nottingham,
Nottingham, United Kingdom,
4
Department
of Neuroradiology, Nottingham University Hospitals NHS
Trust, Nottingham, United Kingdom,
5
Nottingham
University Hospitals NHS Trust, Nottingham, United
Kingdom
BACKGROUND: There are many MRI mimics of MS which can
cause diagnostic uncertainty. FLAIR* allows better
visualisation of white matter lesions and central veins
which are common in MS. We produced a FLAIR* image at 3T
without contrast agent to analyse MS and ischaemic
lesions. METHODS: Two observers compared the ability of
FLAIR* to standard T2*-weighted imaging in detecting
lesions and central veins. RESULTS: FLAIR* could detect
as many lesions and central veins as T2* CONCLUSIONS:
FLAIR* can differentiate MS from ischaemic lesions at 3T
without contrast agent. Prospective studies will
determine if this can be used as an imaging biomarker.
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