Abstract #4326
Searching for new Dementia-related Features within MRI: Keypoint Detection and Description
Elisabeth Sthler 1
1
Department of Computer and Information
Science, University of Konstanz, Konstanz,
Baden-Wrttemberg, Germany
New dementia-related features are presented to
differentiate between various stages of Alzheimers
disease. Prior registration of MRI-scans, possibly
unsuccessful and always time-consuming, is avoided by
employing local invariant features which are independent
of image scale and orientation. Feature detectors are
implemented based on scale-space theory in an
automatized image processing workflow, and tested on a
standardized MRI collection comprising 382 T1 MRI scans
from patients with Alzheimer's Disease or mild cognitive
impairment, and from a control group. The approach is
not only very efficient for processing large datasets,
but also first order statistics of features already
differentiate significantly between classes.
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