Abstract #4285
Lateralization of Temporal Lobe Epilepsy using a Combinational Model of Electroencephalographic and Imaging
Fariborz Mahmoudi 1,2 , Mohammad-Reza Nazem-Zadeh 1 , Jason M. Schwalb 3 , Ellen L. Air 3 , Hassan Bagher-Ebadian 1 , Manpreet Kaur 3 , Rushna Ali 3 , Saeed Shokri 1 , Kost V. Elisevich 4 , and Hamid Soltanian-Zadeh 1,5
1
Departments of Radiology, Research
Administration, Henry Ford Health System, Detroit,
Michigan, United States,
2
Computer
and It Engineering Faculty, Islamic Azad University,
Qazvin Branch, Qazvin, Qazvin, Iran,
3
Departments
of Neurosurgery, Henry Ford Health System, Detroit,
Michigan, United States,
4
Department
of Clinical Neurosciences, Spectrum Health System, Grand
Rapids, Michigan, United States,
5
CIPCE,
School of Electrical and Computer Engineering,
University of Tehran, Tehran, Iran
Mesial temporal lobe epilepsy (mTLE) is the most common
type of refractory focal epilepsy. Concordant
electroencephalographic, neuropsychological and Magnetic
Resonance Imaging (MRI) findings often lateralize the
epileptogenic side permitting surgical resection of the
mesial temporal structures, without further
investigation. In cases of unclear lateralization,
implantation of intracranial electrodes for long term
monitoring (Phase II) is needed to localize the
epileptogenic zone. Unfortunately, Phase II monitoring
may lead to infection, intracranial hemorrhage, and
elevated intracranial pressure. In this study, we have
developed, a combinational model based on imaging and
other diagnostic procedures to try to reduce the need
for Phase II monitoring. Briefly the purpose of this
study is, developing a model that would not only enhance
patient safety, but also would reduce economic burden.
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