Abstract #4235
Spinal fusion induced increase of energy demand in lower back muscles - A functional 31 P-MRS study
Alexander Gussew 1 , Philipp Schenk 2,3 , Heiko Stark 4 , Bernhard Ullrich 3 , Christoph Anders 2 , Patrick Hiepe 1 , Reinhard Rzanny 1 , Kai Wohlfahrt 5 , Gunther Hofmann 2,3 , Hans-Christoph Scholle 2 , and Jrgen R. Reichenbach 1
1
Medical Physics Group, Institute of
Diagnostic and Interventional Radiology, Jena University
Hospital - Friedrich Schiller University Jena, Jena,
Thuringia, Germany,
2
Clinic
for Trauma, Hand and Reconstructive Surgery, Division of
Motor Research, Pathophysiology, Jena University
Hospital - Friedrich Schiller University Jena, Jena,
Thuringia, Germany,
3
Department
of Trauma Surgery, BG Clinics Bergmannstrost, Halle
(Saale), Saxony-Anhalt, Germany,
4
Institute of
Systematic Zoology and Evolutionary Biology,
Friedrich-Schiller-University Jena, Jena, Thuringia,
Germany,
5
Clinic
for Neurology, BG Clinics Bergmannstrost, Halle (Saale),
Saxony-Anhalt, Germany
Functional
31
P-MRS
was performed in five patients after spinal fusion
during a standardized isometric exercise to evaluate
differences of load induced high energy metabolic
alterations in back muscles close to the fused vertebrae
segments. Compared to healthy subjects, patients showed
stronger PCr depletions during exercise indicating
higher energy demand and thus higher muscle stress
(patients: 61 17 % vs. controls: 37 11 %).
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