Abstract #4218
Quantitative Ultrashort TE (UTE) Imaging Predicts Joint Health in Hemophilic Arthropathy
Eric Y Chang 1 , Annette von Drygalski 2 , Thomas J Cramer 2 , Sheronda Statum 3 , Jiang Du 3 , and Christine B Chung 1
1
Radiology Service, VA San Diego Healthcare
System, San Diego, CA, United States,
2
Department
of Hematology/Oncology, University of California, San
Diego Medical Center, San Diego, CA, United States,
3
Department
of Radiology, University of California, San Diego
Medical Center, San Diego, CA, United States
21 patients with hemophilic arthropathy were recruited
for this prospective study. Chronically symptomatic
joints (7 knee, 7 ankle, and 7 elbow joints) were
evaluated using clinical pain and Hemophilia Joint
Health scores as well as conventional and quantitative
3D-UTE-Cones images. Semi-quantitative International
Prophylaxis Study Group (IPSG) MRI scales and UTE-T2*
values of weight-bearing cartilage were calculated and
correlated with clinical scores. We found that UTE-T2*
values of cartilage significantly decrease as joint
health declines in patients with hemophilic arthropathy.
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