Abstract #4194
Relaxation time constants T1 and T2* of bound and free water in cortical bone at 600 MHz and 700 MHz.
Bainan Wu 1 , Robert Nikolov 2 , Hongda Shao 2 , Jun Chen 2 , Graeme Bydder 2 , Maurizio Pellecchia 1 , and Jiang Du 2
1
Sanford-Burnham Medical Research Institute,
La Jolla, California, United States,
2
Radiology,
University of California, San Diego, San Diego,
California, United States
The purpose of this study is to measure and report the
field dependence of NMR relaxation times (T* and T1) of
the free and bound water in cortical bone at magnetic
field strenghts corresponding to frequencies of 600 MHz
and 700MHz. T2* of bound/free water is measured to be
6.2(0.1)s /80(3)s at 600MHz and decreases to
5.4(0.1)s /63(5)s at 700 MHz. T1 of bound/free water
is reported to be 628/632ms at 600 MHz and 661/672 ms at
700 MHz. At both field strengths, the free water
contributes to about 10% of the NMR signal.
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