Abstract #4083
EXTRAMEDULLARY HEMATOPOIESIS IS ASSOCIATED WITH A THALASSAEMIA INTERMEDIA-LIKE PATTERN OF MYOCARDIAL AND LIVER IRON LOADING IN REGULARLY POLYTRANSFUSED THALASSAEMIA PATIENTS
Antonella Meloni 1 , Paolo Ricchi 2 , Paolo Preziosi 3 , Vincenzo Positano 1 , Maria Chiara Resta 4 , Gennaro Restaino 5 , Antonino Vallone 6 , Maria Giovanna Neri 1 , Graziella Filati 7 , Anna Pietrapertosa 8 , Petra Keilberg 1 , and Alessia Pepe 1
1
CMR Unit, Fondazione G. Monasterio
CNR-Regione Toscana, Pisa, Italy,
2
UOSD
Centro per le Microcitemie, AORN Cardarelli, Napoli,
Italy,
3
U.O.C.
Diagnostica per Immagini e Interventistica, Policlinico
Casilino", Roma, Italy,
4
Struttura
Complessa di Radiologia, OSP. SS. Annunziata ASL
Taranto, Taranto, Italy,
5
Istituto
di Radiologia, Universit Cattolica del Sacro Cuore,
Campobasso, Italy,
6
Istituto
di Radiologia, Az. Osp. "Garibaldi" Presidio Ospedaliero
Nesima, Catania, Italy,
7
Pediatria, Ospedale
G. Da Saliceto, Piacenza, Italy,
8
Policlinico
di Bari, Servizio Regionale Talassemie, Bari, Italy
In a large cohort of regularly transfused thalassemia
patients, the presence of extramedullary hematopoiesis
(EMH) assessed by MRI was not rare. EMH was associated
to a heart thalassemia intermedia like pattern (reduced
cardiac iron loading and stigmata of high cardiac output
state) despite the transfusional regimen
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