Abstract #4080
Pancreatic Iron: A Future Major Organ in Iron Overload Diseases - The Role of R2*-Relaxometry
Jin Yamamura 1 , Sarah Keller 1 , Bjrn Schnnagel 1 , Regine Grosse 2 , Zhiyue Jerry Wang 3 , Peter Nielsen 4 , Gerhard Adam 1 , and Roland Fischer 1,5
1
Diagnostic and Interventional Radiology,
University Medical Center Hamburg-Eppendorf, Hamburg,
Hamburg, Germany,
2
Pediatric
Hematology and Oncology, University Medical Center
Hamburg-Eppendorf, Hamburg, Hamburg, Germany,
3
Department
of Radiology, University of Texas Southwestern Medical
Center, Dallas, Texas, United States,
4
Biochemistry,
University Medical Center Hamburg-Eppendorf, Hamburg,
Hamburg, Germany,
5
Department
of Radiology, Children's Hospital & Research Center
Oakland, Oakland, California, United States
This study aims to determine the pancreatic iron and fat
content in patients with iron overload.Highest iron and
fat content was found in the pancreatic tail and
pancreatic R2* correlated with cardiac iron deposition.
Besides iron accumulation, fatty degeneration might be
an additional risk factor for the development of
diabetes and might also explain the early onset of
diabetes in these patients.
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