Abstract #4071
Repeatability of measurement of liver T1, T2 and PDFF by multi-TR, multi-TE single breath-hold 1 H MR spectroscopy.
Gavin Hamilton 1 , Michael S Middleton 1 , William M Haufe 1 , Jonathan C Hooker 1 , Yesenia Covarrubias 1 , Rohit Loomba 2 , and Claude B Sirlin 1
1
Department of Radiology, UC San Diego, San
Diego, California, United States,
2
Department
of Medicine, UC San Diego, San Diego, California, United
States
We developed a rapid multi-TR, multi-TE
1
H
MRS sequence for
in
vivo
hepatic
fat quantification and characterization that acquires 32
single-average spectra in a single breath-hold. We
examined the intra-examination repeatability of the
sequence by repeating it three times in the same
location without patient repositioning. The study showed
that this single-breath-hold, multi-TR, multi-TE
sequence can measure liver water T1 and T2, fat T2, and
proton density fat fraction with high repeatability.
Repeatability for fat T1 was modest.
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