Abstract #4007
The value of Gd-EOB-DTPA enhanced MR imaging in characterizing cirrhotic nodules with atypical enhancement in Gd-DTPA enhanced MRI imaging
Yi-Chun Wang 1,2 , Wen-Pei Wu 2,3 , Cheng-In Hoi 2 , Chen-Te Chou 2,3 , and Ran-Chou Chen 2,4
1
Radiology, taoyuan general hospital ministry
of health and welfare, Taiwan, Taoyuan, Taiwan,
2
Biomedical
Imaging and Radiological Science, National Yang-Ming
Medical University, Taipei, Taiwan,
3
Radiology,
Chang-Hua Christian Hospital, Taiwan,
4
Radiology,
Taipei city Hospital, Taiwan, Taipei, Taiwan
According to AASLD, a diagnosis of HCC can be made by
that a nodule larger than 1.0 cm showed typical
enhancement on dynamic CT or MR. However, up to 44% HCCs
show atypical features on dynamic contrast-enhanced
images. The purpose of this study was to evaluate
whether Gd-EOB-DTPA enhanced hepatocyte phase MR images
can improve the diagnosis of HCC in patients with
atypical enhanced cirrhotic nodules detected on
conventional dynamic MR images. In our study,
hypointense on hepatocyte phase having 83.5% diagnostic
accuracy is superior to the dynamic phases. If we
combine the hypointensity on hepatocyte phase with
arterial hypervascularity, the specificity will be
95.7%. However, when we combined the hypointensity on
hepatocyte phase with arterial isovascularity, the
specificity is only 73.9%.
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