Abstract #3979
Breath-held 3D radial MRI for simultaneous assessment of lung structure and function for detection of pulmonary embolism
Laura C Bell 1 , Peter Bannas 2 , Kevin M Johnson 2 , Grzegor Bauman 3 , Sean B Fain 1,2 , Thomas M Grist 1,2 , and Scott K Nagle 1,2
1
Department of Medical Physics, University of
Wisconsin - Madison, Madison, Wisconsin, United States,
2
Department
of Radiology, University of Wisconsin - Madison,
Madison, Wisconsin, United States,
3
Department
of Radiology, University of Basel Hospital, Basel,
Switzerland
Conventional dynamic contrast-enhanced MR sequences
sacrifice spatial resolution for high temporal
resolution in order to visualize perfusion. This work
utilizes a single breath-held 3D radial UTE acquisition
with both high spatial (to visualize filling defects)
and temporal resolution (to visualize perfusion defects)
to identify pulmonary embolism in an animal model. This
technique performed very well against computed
tomography angiography, collected as a reference.
Additionally, the reader had higher confidence in
diagnosing defects with the 3D radial acquisition due to
better image quality when compared to a typical 3D
Cartesian acquisition.
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