Abstract #3976
Oxygen-Enhanced Ventilation Mapping of Whole Lungs using 3D UTE at 3T
Crystal E. Harrison 1 , Masaya Takahashi 1 , Robert E. Lenkinski 1 , and Ananth J. Madhuranthakam 1
1
Radiology and Advanced Imaging Research
Center, UT Southwestern Medical Center, Dallas, TX,
United States
Chronic obstructive pulmonary disease (COPD) disrupts
pulmonary ventilation and perfusion. Oxygen-Enhanced
(OE) MRI can probe pulmonary ventilation with inhaled
molecular oxygen as an exogenous T
1
contrast
agent. One of the primary challenges of lung imaging is
the short T
2
* of the lung tissue. Ultrashort
echo time (UTE) radial acquisitions minimize this signal
loss and SNR at short TE is higher for 3 T than 1.5 T as
is the change in T
1
due
to inhaled O
2
. The purpose of the current
study is to demonstrate the feasibility of performing
the OE-UTE ventilation mapping in human subjects at 3 T.
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