Abstract #3911
Accelerated Neonatal fMRI using Multiband EPI
Anthony N. Price 1,2 , Lucilio Cordero-Grande 1,2 , Shaihan J. Malik 1,2 , Maryam Abaei 1 , Tomoki Arichi 1 , Emer J. Hughes 1 , Daniel Rueckert 3 , A. David Edwards 1 , and Joseph V. Hajnal 1,2
1
Centre for the Developing Brain, King's
College London, London, United Kingdom,
2
Division
of Imaging Sciences & Biomedical Engineering, King's
College London, London, United Kingdom,
3
Biomedical
Image Analysis Group, Imperial College London, London,
United Kingdom
Simultaneous multi-slice EPI acquisitions using
multiband (MB) excitation have recently been
demonstrated to provide high resolution fMRI data with
significantly reduced acquisition time, sufficient
enough to directly determine cardiac and respiratory
influences from spontaneous activation in the brain.
These have mainly been applied to adult subjects, but
here we demonstrate MB EPI applied to preterm infants
with cardiac rates exceeding 160 bpm. Resting state fMRI
data collected with MB factors of 9 demonstrate it is
possible to distinguish the neonatal cardiac physiology
from activations in resting state networks.
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