Abstract #3884
Multi-parametric MRI in evaluating pre-and post-menopausal ER positive breast cancer
Elizabeth O'Flynn 1 , David Collins 1 , James D'Arcy 1 , Maria Schmidt 1 , and Nandita deSouza 1
1
CRUK Cancer Imaging Centre, The Institute of
Cancer Research, Sutton, Surrey, United Kingdom
The purpose of this study was to compare multiparametric
MRI parameters of ER positive tumours in pre- and
postmenopausal women to assess any differences in tumour
functional characteristics and to establish which
parameter correlated significantly with response as
defined by tumor volume reduction.In premenopausal women
with ER positive breast cancer, tumors were larger and
more vascular than in postmenopausal women. A rise in
the ve correlated significantly with volume reduction in
premenopausal women; no specific parameter correlated
with response in postmenopausal women.
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