Abstract #3753
Improving T 2 * mapping accuracy by spatially adaptive non local means noise filtering
Till Huelnhagen 1 , Andreas Pohlmann 1 , and Thoralf Niendorf 1,2
1
Berlin Ultrahigh Field Facility (B.U.F.F.),
Max-Delbrueck Center for Molecular Medicine (MDC),
Berlin, Germany,
2
Experimental
and Clinical Research Center, a joint cooperation
between the Charite Medical Faculty and the
Max-Delbrueck Center, Berlin, Germany
This works investigates the impact of spatially adaptive
non local means filtering (SANLM) on T
2
*
mapping
accuracy using numerical simulations and in vivo data
derived from animal and human imaging at ultrahigh
magnetic fields. The presented results suggest, that
SANLM filtering prior to T
2
*
mapping
can substantially improve T
2
*
fitting
accuracy, but should be used with due caution for very
small structures and very low SNR. The in vivo results
suggest that SANLM filtering provides means for
improving parametric mapping for a broad range of
applications including neurovasculaar and cardiac
parametric mapping.
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