Abstract #3696
Quantitative 19 F MR Molecular Imaging with B 1 -Mapping Compensation
Matthew Goette 1,2 , Shelton Caruthers 1 , Gregory Lanza 1 , and Samuel Wickline 1
1
Cardiology, Washington University in St.
Louis, St. Louis, MO, United States,
2
Pediatric
Radiology, Texas Children's Hospital, Houston, TX,
United States
This study presents a strategy to more accurately
quantify the sparse
19
F
signal from
3
integrin
targeted perfluorocarbon nanoparticle emulsions with a
1
H
image-based actual flip angle B
1
-mapping
correction to the
19
F
and
1
H
images, acquired with a simultaneous dual-frequency
ultra-short echo time balanced steady state free
precession sequence, in a phantom and an
in
vivo
setting
using a VX2 tumor model implanted into rabbits.
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