Abstract #3694
Simultaneous quantification of intravascular blood T 1 and T 2 with multiple-readout TRUST (mTRUST)
Zachary B Rodgers 1 and Felix W Wehrli 1
1
Radiology, University of Pennsylvania,
Philadelphia, PA, United States
Simultaneous measurement of intravascular blood T
1
and
T
2
is
a promising approach for fast, accurate quantification
of whole-brain venous oxygen saturation (Y
v
),
as the T
1
values
can be used to determine hematocrit, which is needed to
convert measured T
2
to
Y
v
. We describe a modification of the
recently developed TRUST T
2
-quantification
method, with addition of multiple EPI readouts (mTRUST)
to allow concurrent measurement of T
1
. mTRUST
was applied in four subjects, demonstrating good
precision for T
1
and
T
2
estimation.
T
1
values
were slightly lower than recent literature, potentially
due to incomplete inversion of blood present in the
later EPI readouts.
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