Abstract #3690
Fast Aortic Input Function Extraction at High Temporal Resolution for DCE-MRI
Umit Yoruk 1,2 , Manojkumar Saranathan 1 , Tao Zhang 1 , Brian A Hargreaves 1 , and Shreyas S Vasanawala 1
1
Radiology, Stanford University, Stanford,
CA, United States,
2
Electrical
Engineering, Stanford University, Stanford, CA, United
States
Many pharmacokinetic models in DCE-MRI need
subject-based aortic input function (AIF). Accurate AIF
measurement requires high temporal resolution images,
which compromises the image spatial resolution. A
recently developed low-rank reconstruction technique
allows reconstruction of two sets of images, a high
temporal resolution image for quantitative analysis and
a high spatial resolution image for clinical evaluation,
at a cost of increased reconstruction time. We present a
faster method for extracting high temporal resolution
AIF from DCE-MRI data and compare it to the low-rank
reconstruction. The feasibility of this method was
demonstrated on a pediatric subject.
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