Abstract #3510
Reliability, Power, and Calibration for Multisite MRI Volumetric Studies
Anisha Keshavan 1 , Friedmann Paul 2 , Mona Beyer 3 , Rohit Bakshi 4 , Phillip De Jager 4 , Massimo Filippi 5 , David Hafler 6 , Hanne Harbo 3 , Stephen Hauser 1 , Ludwig Kappos 7 , Filippo Martinelli 5 , Daniel Pelletier 6 , Maria Rocca 5 , Till Sprenger 7 , William Stern 1 , Bernard Uitdehaag 8 , Mike Wattjes 8 , Howard Weiner 4 , Jens Wrfel 2 , Alyssa Zhu 1 , Jorge Oksenberg 1 , and Roland Henry 1
1
Neurology, UCSF, San Francisco, CA, United
States,
2
Charit
Universittsmedizin, Germany,
3
Oslo
University Hospital, Norway,
4
Brigham
and Women's Hospital, MA, United States,
5
Scientific
Institute Ospedale San Raffaele, Italy,
6
Yale
University, CT, United States,
7
University
Hospital, Basel, Switzerland,
8
Academic
Hospital Vrije Universiteit, Netherlands
Acquiring data using non-standardized protocols could
provide a cost and implementation efficient strategy for
multisite MRI volumetric studies. We demonstrate
feasibility and power considerations for such studies
using a unique cohort of travelling controls across 8
institutions in the USA and Europe.
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