Abstract #3455
Examining the Relationships between Cortical Maturation and White Matter Myelination throughout Early Childhood
Elise Croteau-Chonka 1 , Justin Remer 2 , Jonathan O'Muircheartaigh 3 , Holly Dirks 2 , Doug Dean III 4 , and Sean Deoni 2
1
Advanced Baby Imaging Lab, Brown University,
Providence, Rhode Island, United States,
2
Advanced
Baby Imaging Lab, Brown University, Rhode Island, United
States,
3
King's
College London, England, United Kingdom,
4
Waisman
Center, University of Wisconsin-Madison, Wisconsin,
United States
Two important neurodevelopmental processes that occur
throughout infancy and early childhood are the
maturation of the myelinated white matter and cortical
development (including changes in thickness, surface
area, gyrification, and volume). Few prior studies have
investigated the relationship between these two
processes. Here, we investigate these related processes
for the first time in a large cohort of young children
1-6 years of age. We show that, while related, cortical
thickness and adjacent white matter maturation are not
proxies for one another in this age group.
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