Abstract #3441
Resting State Network Development in Very Preterm Infants
Lili He 1 and Nehal A. Parikh 1,2
1
Center for Perinatal Research, The Research
Institute at Nationwide Children's Hospital, Columbus,
Ohio, United States,
2
Department
of Pediatrics, The Ohio State University College of
Medicine, Columubs, Ohio, United States
Resting-state functional connectivity MRI is a task-free
tool that can be safely performed in infants soon after
birth to gain insights into functional brain networks
associated with motor, cognitive, and behavioral
development. In our present longitudinal study, we
followed a cohort of very preterm infants soon after
birth to identify the perinatal developmental windows
for major resting state networks and explore their
maturation through three months corrected age. We
observed the presence of several important networks,
resembling patterns observed in adults, in very preterm
infants. Additionally, most of the networks demonstrated
an increase in connection strength with advancing
postnatal age.
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