Abstract #3427
PET attenuation correction for PET/MR by combining MR segmentation and selective-update joint estimation
Lishui Cheng 1 , Sangtae Ahn 1 , Dattesh Shanbhag 2 , Florian Wiesinger 3 , Sandeep Kaushik 2 , and Ravindra Manjeshwar 1
1
GE Global Research, Niskayuna, NY, United
States,
2
GE
Global Research, Bangalore, India,
3
GE
Global Research, Munich, Germany
Attenuation correction is critical to accurate PET
quantitation. In PET/MR, MR-based attenuation correction
(MR-AC) has challenges in bone, air, lung and implant
regions. To address the problem, we combined 1) a
segmentation-based MR-AC method, which works well in
soft-tissue regions, and 2) a selective-update joint
estimation approach, which reconstructs both attenuation
and activity from PET emission data, to resolve the
attenuation in the challenging regions. The method was
evaluated on clinical data from a PET/MR scanner with
TOF information and it was demonstrated that the method
can distinguish between abdominal air and spinal
implant/bone regions, otherwise hidden in MR.
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