Abstract #3312
DirEct Complex signAl Fitting (DECAF) for multi-compartment analysis in white matter
Yoonho Nam 1 , Dong-Hyun Kim 2 , and Jongho Lee 1
1
Department of Electrical and Computer
Engineering, Seoul National University, Seoul, Seoul,
Korea,
2
Department
of Electrical and Electronic Engineering, Yonsei
University, Seoul, Korea
Recent studies have demonstrated that signals from three
water compartments in white matter have different B0
orientation dependent frequency offsets. This
observation improved data fitting results in GRE-based
MWI by using complex signal fitting as compared to
magnitude signal fitting. However, the complex signal
fitting approaches applied in the previous studies
required several pre-processing steps including a
nonlocal background field removal step. Therefore, the
results were strongly influenced by them. In this study,
we propose a new fitting method that does not require a
prior background field removal step. This method shows
improvement in parameter estimation.
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