Abstract #3263
Synthetic MP-RAGE anatomies with pure T1-weighting improve the detectability of brain tumors
Ulrike Noeth 1 , Elke Hattingen 2 , Oliver Baehr 3 , Julia Tichy 3 , and Ralf Deichmann 1
1
Brain Imaging Center (BIC), Goethe
University Frankfurt/Main, Frankfurt/Main, Germany,
2
Institute
of Neuroradiology, University Hospital Frankfurt/Main,
Germany,
3
Dr
Senckenberg Institute of Neurooncology, Goethe
University Frankfurt/Main, Germany
Synthetic MP-RAGE anatomies were calculated from
quantitative parameter maps (T1, PD, and RF coil bias)
and the influence of these parameters on MP-RAGE image
contrasts is discussed. Acquired and synthetic data are
analyzed for SNR, CNR, and optical contrasts. In
contrast to conventional anatomies with mixed contrasts,
purely T1-weighted synthetic anatomies show
significantly higher optical contrasts and improved
visibility of tumor and edema in patients with high
grade glioma.
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