Abstract #3255
Efficient maximum likelihood estimation of T 1 , T 2 *, and flip angle error using variable-length echo trains in combined AFI and FLASH experiments
M. Dylan Tisdall 1,2 and Andr J. W. van der Kouwe 2,3
1
Martinos Center for Biomedical Imaging,
Massachusetts General Hospital, Charlestown,
Massachusetts, United States,
2
Radiology,
Harvard Medical School, Boston, MA, United States,
3
Martinos
Center for Biomedical Imaging, Massachusetts General
Hospital, Charlestown, MA, United States
We demonstrate the addition of variable length echo
trains to AFI to improve the SNR/time of the scan,
reduce distortions due to B
0
inhomogeneity,
and allow for accurate T
2
*
mapping.
We also introduce a novel, highly efficient algorithm
for finding the maximum likelihood estimate of T1 and
flip angle scaling error from the multi-echo data.
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