Abstract #3158
T 1 - and TR-Independent B 1 + Mapping by Bloch-Siegert Shift for 7T Human Cardiac 31 P-MRS
William T Clarke 1 , Matthew D Robson 1 , and Christopher T Rodgers 1
1
OCMR, RDM Cardiovascular Medicine,
University of Oxford, Oxford, United Kingdom
Human Cardiac
31
P-MRS
at 7T suffers from low peak B
1
, making B
1
insensitive
adiabatic or composite pulses impossible. Accurate B
1
values
are required to correct partially saturated metabolite
amplitudes and ratios. Long T
1
s and 3D-CSI
acquisition makes magnitude B
1
mapping
approaches infeasible. Bloch-Siegert shift B
1
mapping
is insensitive to metabolite T
1
s and sequence
TR. In this work Bloch-Siegert mapping is validated
against gold standards in phantoms and against a
previously published dual TR method in skeletal muscle.
The feasibility of the approach for cardiac
31
P-MRS
is demonstrated in a single subject.
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