Abstract #3069
'Whole-Body PET/MR Imaging: Quantitative Evaluation of a Novel Model-based MR Attenuation Correction Method Including Bone
Daniel H Paulus 1 , Harald H Quick 1,2 , Matthias Fenchel 3 , Christian Geppert 3 , David Faul 4 , Yiqiang Zhan 5 , Fernando E Boada 6,7 , Kent L Friedman 6 , and Thomas Koesters 6,7
1
Institute of Medical Physics, University of
Erlangen-Nrnberg, Erlangen, Germany,
2
High
Field and Hybrid MR Imaging, University Hospital Essen,
Essen, Germany,
3
Siemens
AG Healthcare, Erlangen, Germany,
4
Siemens
AG Healthcare, New York, NY, United States,
5
Siemens
AG Healthcare, Malvern, PN, United States,
6
NYU
Langone Medical Center, Center for Biomedical Imaging,
Department of Radiology, New York, NY, United States,
7
NYU
Langone Medical Center, Center for Advanced Imaging
Innovation and Research, CAI2R, New York, NY, United
States
In whole-body hybrid PET/MR imaging, bone is currently
disregarded in attenuation correction. For head imaging,
several approaches have been proposed to consider bone,
but yet, not assigned to whole-body imaging. A novel
attenuation correction approach for hybrid PET/MR
imaging is presented and evaluated on 19 patients that
combines the routine Dixon-based soft tissue
segmentation with model-based bone estimation for
whole-body imaging. As a standard of reference, CT
images of each patient were non-rigidly registered to
the MR images. It is shown that the new method
significantly improves the PET quantification in bony
tissue, bone lesions, and tissue close to bone.
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