Abstract #3032
Effect of diffusion and vessel topology on relaxation mechanisms using a cylinder fork model
Mohammed Salman Shazeeb 1 and Bashar Issa 1
1
Department of Physics, UAE University, Al-Ain,
Abu Dhabi, United Arab Emirates
Straight cylinders are conventionally used when
simulating BOLD contrast effects in fMRI. But the
vasculature is more complicated with branching and
coiling especially in tumors which can affect relaxation
times. Diffusion can also introduce changes in the
relaxation mechanisms within tumors. In this study, we
use a simple cylinder fork model to reflect the
curvature of vessels and performed simulations at
different diffusion rates to study the effect of the
bifurcation angle and diffusion on transverse relaxation
times. This model clearly indicated a dependence of
relaxation times on the bifurcation angle which varied
between low and high diffusion constants.
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