Abstract #3012
Whole Body diffusion-weighted MRI: Normal lymph node distribution, volume and apparent diffusion coefficient (ADC) in healthy volunteers
Raphael Shih Zhu Yiin 1 , Giuliano Scattoli 1 , Dow-Mu Koh 1 , David J Collins 2 , Martin O Leach 2 , and Matthew D Blackledge 2
1
Department of Radiology, The Royal Marsden
Hospital, Sutton, Surrey, United Kingdom,
2
CR-UK
and EPSRC Cancer Imaging Centre, Sutton, Surrey, United
Kingdom
Whole body diffusion weight imaging (WB-DWI) is being
used to evaluate nodal disease in lymphoma and
metastatic nodal disease. However, there is an overlap
in the MR diffusion properties of malignant and
non-malignant lymph nodes. An improved understanding of
the DWI characteristics of normal lymph nodes would
inform disease assessment. Our study established the
whole body distribution of normal lymph nodes and showed
the mean ADC value for the nodes to be similar to other
published studies. We also defined the full ADC
histogram characteristics of normal lymph nodes, which
may inform future disease assessment when compared with
diseased states.
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