Abstract #2993
Ventral Intermediate Nucleus (VIM) Localization with Probablistic Diffusion Tractography
Chia-Chu Chou 1,2 , Prashant Raghavan 1 , Dheeraj Gandhi 1 , Rao P Gullapalli 1 , and Jiachen Zhuo 1
1
Diagnostic Radiology and Nuclear Medicine,
University of Maryland School of Medicine, Baltimore,
Maryland, United States,
2
Electrical
and Computer Engineering, University of Maryland,
College Park, Maryland, United States
Thalamotomy targeting VIM has been proved to be an
efficient treatment against tremor. However, the
localization process for VIM is challenging. Atlas-based
coordinate methods commonly adopted does not account for
patient specific anatomy variation. In this study, we
showed preliminary evidence that we can use
probabilistic tractography to identify cortical region
that has unique connectivity with VIM in the thalamus.
Our tracked VIM region from cortical connectivity showed
good correspondence (67% volume overlap) with the altas-based
VIM mask. We expect this new method can further
facilitate the process of future thalatomy surgical
planning.
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