Abstract #2961
Cardiac-triggered pCASL: A cost-effective scheme to enhance the SNR of ASL
Yang Li 1 , Deng Mao 1 , and Hanzhang Lu 1
1
Advanced Imaging Research Center, University
of Texas Southwestern Medical Center, Dallas, Texas,
United States
The current recommended protocol for ASL is to use
pseudocontinuous labeling with 3D acquisition after
background suppression. With the recommended long
labeling time (1.8s) and post-labeling delay time
(1.8s), it is generally thought that the effect of
cardiac pulsation should be minimal. However, we often
observe the existence of large fluctuations in the
difference image (control-label) intensity from one
volume to another. Here, we show that the global signal
fluctuations is largely attributed to cardiac phase
differences from one volume to another, and that
cardiac-gated pCASL can increase the SNR by 79% at a
modest cost of scan time.
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