Abstract #2949
Constrained optimization of gradient waveforms for isotropic diffusion encoding
Jens Sjlund 1,2 , Markus Nilsson 3 , Daniel Topgaard 3 , Carl-Fredrik Westin 1,4 , and Hans Knutsson 1,5
1
Linkping University, Linkping, Sweden,
2
Elekta
Instrument AB, Stockholm, Sweden,
3
Lund
University, Sweden,
4
Brigham
and Womens Hospital and Harvard Medical School, MA,
United States,
5
Center
for Medical Image Science and Visualization (CMIV),
Linkping, Sweden
We propose a new framework for numerical optimization of
diffusion encoding gradient waveforms. The formulation
allows explicit control of hardware requirements,
including maximum gradient amplitude, slew rate, heating
and positioning of RF pulses. The power of the approach
is demonstrated by a comparison with previous work on
optimization of isotropic diffusion sequences, showing
possible gains in diffusion weighting or in heat
dissipation.
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