Abstract #2942
Effects of slab boundary artifacts on diffusion measures in 3D multi-slab diffusion imaging
Wenchuan Wu 1 , Peter Koopmans 1 , and Karla L Miller 1
1
FMRIB Centre, Nuffield Department of
Clinical Neurosciences, University of Oxford, Oxford,
Oxfordshire, United Kingdom
3D multi-slab diffusion imaging suffers from slab
boundary artifacts. If the effects were purely
multiplicative, the calculation of diffusion measures
should not be affected after normalization by the b=0
image. However, several studies have shown slab boundary
artifacts in diffusion tensor metrics. In this work, we
investigated the effects of saturation, partial volume
and B0 inhomogeneity on slab boundary artifacts and
diffusion tensor measures (ADC and FA). We found that
the slab boundary artifacts are modulated by many
factors, which may not be effectively normalized by b=0
image and result in errors in diffusion measures.
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