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Abstract #2937

Intrinsic Diffusion Sensitivity of the bSSFP Signal: Optimizing the flip angle in the presence of Strong Read Out Gradients

Sbastien Br 1 , Matthias Weigel 2 , Jrgen Hennig 1 , Dominik Von Elverfeldt 1 , and Jochen Leupold 1

1 Department of Radiology, Medical Physics, University Medical Center, Freiburg, Freiburg, Germany, 2 Radiological Physics, University of Basel Hospital, Basel, Switzerland

In application fields of bSSFP, like MR-microscopy or molecular imaging, strong gradients mostly available at ultra-high field small animal scanners, are necessary in order to achieve sub-milimeter image resolutions. Due to relatively high b-values of these gradients, strong diffusion effects are induced and particularly read out gradients lead to a substantial drop of the steady state signal. In this work, we demonstrate the optimization of the flip angle in dependency of T 1 , T 2 and b-value of the readout gradient in a standard bSSFP sequence.

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