Abstract #2915
Inner Field of View Diffusion Kurtosis Imaging (DKI) of the Pediatric Spinal Cord
Chris J Conklin 1,2 , Devon M Middleton 2,3 , Jrgen Finsterbusch 4 , Mahdi Alizadeh 2,3 , Scott H Faro 2,3 , Pallav Shah 2 , Laura Krisa 5,6 , Rebecca Sinko 6 , Joan Z Delalic 1 , MJ Mulcahey 6 , and Feroze B Mohamed 2,3
1
Electrical Engineering, Temple University,
Philadelphia, PA, United States,
2
Radiology,
Temple University, Philadelphia, PA, United States,
3
Bioengineering,
Temple University, Philadelphia, PA, United States,
4
Systems
Neuroscience, University Medical Center
Hamburg-Eppendorf, Hamburg, Germany,
5
Physical
Therapy, Thomas Jefferson University, Philadelphia, PA,
United States,
6
Occupational
Therapy, Thomas Jefferson University, Philadelphia, PA,
United States
This work investigates Diffusion Kurtosis Imaging (DKI)
of the pediatric spinal cord using an inner Field of
View (iFOV) sequence. DKI offers the potential to probe
the underlying tissue microstructure by looking at the
non-Gaussianity of water displacement. Both normal and
Spinal Cord Injured (SCI) patients between the ages of 6
and 16 were acquired and analyzed. FA values were
comparable to that shown in current literature and
statistically significant differences were found in
kurtosis metrics between groups. The results are
encouraging and warrant additional study with a larger
population.
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