Abstract #2902
A Framework to calculate the IVIM signal for different diffusion gradient profiles
Andreas Wetscherek 1 and Frederik Bernd Laun 1
1
Medical Physics in Radiology, German Cancer
Research Center (DKFZ), Heidelberg, Germany
Normalized phase distributions for a variety of gradient
profiles (bipolar, flow-compensated, sine, cosine) have
been obtained by simulations, which allow one to
calculate the IVIM signal for given b-value, diffusion
time T, vessel segment length l and blood flow velocity
v. Attenuation curves for a network of blood vessels are
calculated for typical dimensions of arterioles and
capillaries. Signal attenuation is less strong for
flow-compensated profiles, where cosine gradients are
found to show the largest spread of attenuation curves
depending on oscillation number. The source code and
simulated phase distributions are made available online
to the IVIM community.
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