Abstract #2881
Eddy Current Compensation for Double Wave Vector Diffusion MRI
Lars Mller 1 , Andreas Wetscherek 1 , and Frederik Bernd Laun 1
1
Medical Physics in Radiology, German Cancer
Research Center (DKFZ), Heidelberg, Germany
Double wave vector diffusion MRI gives the opportunity
to measure microscopic anisotropy, what, however,
requires to reliably acquire diffusion weighted images
with many diffusion encoding directions. This in turn
might lead to problems in determining trustworthy values
because of eddy current induced image distortions. We
present a sequence design that compensates for eddy
currents, by using additional refocussing pulses and
bipolar gradients. We show the effectivity of our
sequence by determining the coefficient of variation of
the signal intensity over 36 diffusion direction
combinations. Additionally we present evidence that eddy
current compensation is needed to determine reliable
anisotropy values in-vivo.
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