Abstract #2879
In vivo diffusion tensor imaging and tractography of human brain at submillimeter isotropic resolution on a clinical MRI scanner
Mark Sundman 1 , Hing-Chiu Chang 1 , Laurent Petit 2 , Shayan Guhaniyogi 1 , Christopher Petty 1 , Allen Song 1 , and Nan-kuei Chen 1
1
Brain Imaging and Analysis Center, Duke
University Medical Center, Durham, North Carolina,
United States,
2
Groupe
d'Imagerie Neurofonctionnelle (GIN) - UMR5296, CNRS, CEA,
Universit de Bordeaux, Bordeaux, France
This research introduces a novel mothed for
high-resolution diffusion tensor imaging (DTI) that is
capable of achieving submillimeter isotropic resolution
(0.85 x 0.85 x 0.85 mm3) in vivo for the human brain
using a normal 3T clinical scanner. This high-resolution
DTI enables both researchers and physicians to more
accurately identify white matter structures and fiber
tracts in vivo. To demonstrate its utility and
potential, we identified structures at this
submillimeter isotropic resolution that are
indiscernible at conventional resolutions.
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