Abstract #2791
Minimizing Diffusion Encoding of Slice Selection in Stimulated Echo Imaging
Paul Kinchesh 1 , Michiel Kleinnijenhuis 2 , Karla L Miller 2 , and Sean C Smart 1
1
Department of Oncology, University of
Oxford, Oxford, United Kingdom,
2
FMRIB
Centre, Nuffield Department of Clinical Neurosciences,
University of Oxford, United Kingdom
Diffusion weighted stimulated echo imaging is often used
for diffusion encoding with very high b-values and long
diffusion times. For long diffusion times a significant
bias can be introduced through the diffusion encoding
effect of the slice selection gradients. Compensation of
this effect has recently been achieved by adjustment of
the prescribed diffusion encoding gradients, but the
adjustment is specific to the exact choice of
experimental parameters. This report demonstrates that
the effect can be minimized through reduction of the
diffusion encoding effect of the slice selection
gradients themselves, thereby maintaining the fidelity
of any applied diffusion encoding scheme.
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