Abstract #2750
The effect of resolution on viscous dissipation measured with 4D-flow MRI in patients with Fontan circulation: Evaluation using computational fluid dynamics
Merih Cibis 1 , Kelly Jarvis 2,3 , Michael Markl 2,3 , Michael Rose 2,4 , Cynthia Rigsby 2,4 , Alex J Barker 2 , and Jolanda J Wentzel 1
1
Biomedical Engineering, Erasmus MC,
Rotterdam, Netherlands,
2
Radiology,
Northwestern University, Chicago, Illinois, United
States,
3
Biomedical
Engineering, Northwestern University, Chicago, Illinois,
United States,
4
Medical
Imaging, Ann& Robert H Lurie Childrens Hospital of
Chicago, Chicago, Illinois, United States
Viscous dissipation inside Fontan circuit might be
associated with the exercise performance of Fontan
patients. Information on viscous dissipation might
therefore be used in clinical assessment of these
patient and can be calculated in-vivo by using flow MRI
data. However the magnitude of viscous dissipation might
depend on the spatial resolution of the MRI data. We
investigated the influence of resolution on the
estimated viscous dissipation. By using computational
fluid dynamics (CFD) simulations, we showed that
decreased spatial resolution results in underestimated
viscous dissipation. However we were able to capture the
differences in viscous dissipation between patients also
at lower spatial resolution.
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