Abstract #2687
Quantitative First-Pass Perfusion with Whole-Ventricle Coverage Using 3D Through-Time Spiral GRAPPA
Johannes Tran-Gia 1,2 , Jesse Hamilton 2 , David Lohr 1 , Kestutis Barkauskas 2 , Andreas M. Weng 1 , Herbert Kstler 1 , and Nicole Seiberlich 2
1
Department of Diagnostic and Interventional
Radiology, University of Wrzburg, Wrzburg, Germany,
2
Biomedical
Engineering, Case Western Reserve University, Cleveland,
Ohio, United States
A technique is presented for the absolute quantification
of myocardial perfusion in a 3D volume covering the
whole ventricle using contrast-enhanced myocardial
first-pass perfusion imaging. After the contrast agent
injection, a highly accelerated 3D volume is acquired
for each consecutive heartbeat using a
saturation-recovery prepared FLASH sequence with a
stack-of-spirals trajectory. After the acquisition,
missing data are reconstructed by applying parallel
imaging in all spatial dimensions. By applying a
dual-bolus approach, an unsaturated arterial input
function is determined, and absolute perfusion values
are quantified in the entire myocardium.
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