Abstract #2681
Intraindividual comparison of different contrast agent application schemes and their influence on concentration, signal and bolus geometry
Harald Kramer 1,2 , Gregor Jost 3 , Hubertus Pietsch 3 , and Maximilian F Reiser 1
1
Department of Clinical Radiology, University
of Munich, Munich, Bavaria, Germany,
2
Department
of Radiology, University of Wisconsin - Madison,
Madison, Wisconsin, United States,
3
MR
and CT Contrast Media Research, Bayer Healthcare,
Berlin, Berlin, Germany
Although contrast enhanced (CE) techniques are well
accepted as the standard of reference for most magnetic
resonance angiography (MRA) applications, very little is
known about the influence of contrast agent (CA)
application schemes on CA bolus shape. Unlike iodinated
CAs in computed tomography angiography (CTA) or
conventional digital subtraction angiography (DSA),
gadolinium (Gd) based CAs (GBCA) have a non-linear
relationship between CA-concentration and MR signal.
Published CA application approaches are highly variable
between institutions and are based on anecdotal evidence
only.
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