Abstract #2658
In vivo quantification and correlation of intracranial aneurysm wall thickness and wall shear stress
Roos Blankena 1,2 , Rachel Kleinloog 1 , Pim van Ooij 3 , Bon Verweij 1 , Bennie ten Haken 2 , and Jaco Zwanenburg 4
1
Neurology and Neurosurgery, Brain Center
Rudolf Magnus, University Medical Center Utrecht,
Utrecht, Utrecht, Netherlands,
2
Technical
Medicine, University of Twente, Enschede, Overijssel,
Netherlands,
3
Biomedical
Engineering & Physics, Academic Medical Center,
Amsterdam, Noord-Holland, Netherlands,
4
Radiology,
University Medical Center Utrecht, Utrecht, Utrecht,
Netherlands
In-vivo assessment of the aneurysm wall thickness in
combination with wall shear stress (WSS), may provide
new insights in the development of the aneurysm. Using
high-resolution 7T images of the vessel wall, in vivo
aneurysm wall thickness was compared with WSS, obtained
from PCA measurements. A preliminary analysis was
performed, including 9 unruptured aneurysms of 7
patients. All analysed patients showed variations in
wall thickness. A negative correlation between local
wall thickness and WSS was found in almost all
aneurysms. This is the first study presenting a
correlation of local wall thickness with WSS from in
vivo measurements.
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