Abstract #2631
Prospective Changes of Cardiac and Hepatic Iron and Cardiac Function in Low and Intermediate-1 Risk MDS Patients
Antonella Meloni 1 , Michele Rizzo 2 , Giovanni Carulli 3 , Esther Natalie Oliva 4 , Francesco Arcioni 5 , Sergio Storti 6 , Maria Giovanna Neri 1 , Stefania Renne 7 , Emanuele Grassedonio 8 , Gennaro Restaino 9 , Vincenzo Positano 1 , and Alessia Pepe 1
1
CMR Unit, Fondazione G. Monasterio
CNR-Regione Toscana, Pisa, Italy,
2
Reparto
di Ematologia, Azienda Sanitaria Provinciale
Caltanissetta - Ospedale Sant'Elia, Caltanisetta,
Italy,
3
Dip.
di Oncologia, dei Trapianti e delle Nuove Tecnologie in
Medicina Divisione di Ematologia, Facolt di Medicina
e chirurgia Universit degli Studi di Pisa, Pisa,
Italy,
4
Hematology Unit, A.O.
Bianchi-Melacrino-Morelli, Reggio Calabria, Italy,
5
Dipartimento
di Medicina Clinica e Sperimentale, Universit degli
Studi di Perugia, Perugia, Italy,
6
UOC
di Onco-Ematologia, Universit Cattolica del Sacro
Cuore, Campobasso, Italy,
7
Struttura
Complessa di Cardioradiologia-UTIC, P.O. Giovanni Paolo
II, Lamezia Terme, Italy,
8
Dipartimento di
Radiologia, Policlinico "Paolo Giaccone", Palermo,
Italy,
9
Dipartimento
di Radiologia, Universit Cattolica del Sacro Cuore,
Campobasso, Italy
The aim of our study was to assess the changes in
cardiac and hepatic iron overload and the
morpho-functional cardiac parameters by MRI in
myelodysplastic patients who performed the follow-up
(FU) MRI at 12 months. The new occurrences of cardiac
iron, reduced cardiac function, increased LV and RV EDVI
and myocardial fibrosis and the worsening in MRI LIC
(liver iron concentration) values suggest the need of
performing periodic MRI scans, in order to better manage
these patients.
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