Abstract #2620
Non-contrast characterization of interstitial cardiac remodeling in chronic kidney disease patients
Tori A Stromp 1 , Steve W Leung 2,3 , Vincent L Sorrell 2,3 , and Moriel H Vandsburger 1,2
1
Department of Physiology, University of
Kentucky, Lexington, KY, United States,
2
Saha
Cardiovascular Research Center, University of Kentucky,
Lexington, Kentucky, United States,
3
Gill
Heart Institute, University of Kentucky, Lexington, KY,
United States
Patients with chronic kidney disease are at high risk
for adverse cardiac events with an emerging link to
fibrosis. While such patients would benefit from
diagnosis with LGE, they are contraindicated due to
safety concerns. We compared two methods of non-contrast
cardiac MRI to identify interstitial remodeling in a
patient population on routine hemodialysis for CKD. Both
native T1 mapping and our previously developed cine
bSSFP method (termed 2-point bSSFP) showed greater
enhancement patterns in patients with CKD compared to
healthy controls, indicating areas of interstital
remodeling.
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