Abstract #2598
Combination of T2-Magnetization Preparation and Slice Interleaved Inversion Recovery for Improved Motion Correction of Myocardial Extra-cellular Volume Mapping using Spoiled Gradient Echo Imaging
Sbastien Roujol 1 , Tamer A. Basha 1 , Jihye Jang 1 , Kraig V. Kissinger 1 , Beth Goddu 1 , Sophie Berg 1 , Warren J. Manning 1,2 , and Reza Nezafat 1
1
Department of Medicine, Beth Israel
Deaconess Medical Center and Harvard Medical School,
Boston, Massachusetts, United States,
2
Department
of Radiology, Beth Israel Deaconess Medical Center and
Harvard Medical School, Boston, Massachusetts, United
States
Myocardial extracellular volume fraction (ECV) mapping
requires co-registration of native and post-contrast T1
maps, generally acquired with a b-SSFP readout. However
the b-SSFP signal is susceptible to B0 field
inhomogeneity, T2 dependent, and sensitive to
magnetization transfer. To overcome these limitations,
slice interleaved inversion recovery spoiled gradient
echo (GRE) imaging has been recently proposed for T1
mapping. However, the co-registration of native and
post-contrast GRE T1 scans is challenging since short
inversion time (TI) images have very different
intensity/contrast between pre/post-contrast imaging and
long TI images have low blood/myocardium contrast. In
this study, we sought to develop and evaluate a combined
T2-magnetization preparation imaging and slice
interleaved inversion recovery spoiled gradient echo
imaging to facilitate the co-registration process and
improve ECV mapping.
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