Abstract #2585
High Resolution In Vivo Cardiac MRI of Zebrafish With An Integrated Coil Flow Cell Design
Gavin D Merrifield 1 , Lindsay Gallagher 1 , James Mullin 1 , Carl S Tucker 2 , Maurits A Jansen 2,3 , William M Holmes 1 , and Martin A Denvir 2
1
Glasgow Experimental MRI Centre, University
of Glasgow, Glasgow, Glasgow, United Kingdom,
2
University
of Edinburgh/British Heart Foundation Centre for
Cardiovascular Science, University of Edinburgh,
Edinburgh, Midlothian, United Kingdom,
3
Edinburgh
Preclinical Imaging, University of Edinburgh, Edinburgh,
Midlothian, United Kingdom
As an emerging biomedical model the development of
Magnetic Resonance Imaging techniques for use in the
zebrafish would prove particularly useful to many
streams of in vivo research. However the exceptionally
small size of this species compared to rodent models and
it's unique aquatic environment provide several
practical challenges to be overcome. We present a custom
MRI compatible flow cell equipped with an integrated
solenoid coil for successful imaging that meet those
challenges.
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