Abstract #2555
Prospective Motion Correction (PROMO) enabled MP2RAGE for multi-contrast high-resolution brain imaging
Alexandru V. Avram 1 , Joelle E. Sarlls 2 , Cibu P. Thomas 1,3 , Vinai Roopchansingh 4 , Dan Rettmann 5 , Ajit Shankaranarayanan 6 , and Peter J. Basser 1
1
Section on Tissue Biophysics and
Biomimetics, NICHD, National Institutes of Health,
Bethesda, MD, United States,
2
NINDS,
National Institutes of Health, Bethesda, MD, United
States,
3
The
Henry Jackson Foundation, Bethes, MD, United States,
4
NIMH/Functional
MRI Facility, National Institutes of Health, Bethesda,
MD, United States,
5
ASL,
GE Healthcare, Rochester, MN, United States,
6
ASL,
GE Healthcare, Menlo Park, CA, United States
Images with different tissue contrasts acquired with the
MP2RAGE pulse sequence, although inherently
co-registered, can suffer from imaging artifacts due to
subject motion especially in studies involving
non-compliant subjects such as pediatric or elderly
patient populations. We implement a PROMO-enabled 3D
MP2RAGE pulse sequence, evaluate its ability to correct
for subject motion, and illustrate how it can be used
for multi-contrast high-resolution tissue visualization
and characterization in moving subject at 3T.
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