Abstract #2428
Sensitivity improvement under parallel detection in CW-EPR imaging
Ayano Enomoto 1 and Hiroshi Hirata 1
1
Division of Bioengineering and
Bioinformatics, Hokkaido University, Sapporo, Hokkaido,
Japan
The purpose of this study was to improve the
signal-to-noise ratio (SNR) in the parallel EPR
detection scheme using multiple channels and to
demonstrate the feasibility of in vivo EPR imaging with
parallel EPR detection. This improvement in sensitivity
leads to a decrease in the image acquisition time in
three-dimensional EPR imaging. EPR imaging of
3-carbamoyl-2,2,5,5-tetramethylpyrrolidine-1-oxyl (3-CP)
in a subject mouse was demonstrated with a surface coil
array and a parallel detection scheme. In addition to in
vivo mouse imaging, tests were also performed with
phantoms filled with nitroxyl radical solutions.
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